From
the West:
If you are coming from Witchita, Kansas City, St.
Louis and Nashville, take I-70 to I-64 (through St. Louis). Continue
I-64 to I-57 to I-24 and the I-40 east (through Nashville). Stay
on I-40 east and exit 364 S.R. 95. Go east on 321 through Maryville
and Townsend. where you enter the Park from the Townsend side of
the Smokies, near Cades Cove.